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We offer two products for use in process development and production in the area of depth filtration. The PendoTECH Filter Screening System can be used for process optimization of filtration processes such as a filtration train used for cell harvest after a bioreactor and/or centrifuge. The PendoTECH Depth Filtration System can be used for process control and process monitoring of a depth filtration process at any scale.
Our Filter Screening System is for filtration sizing and optimization studies, up to 4 filter trains with 3 PendoTECH Pressure Sensors each (12 total) can be monitored so multiple filters can be compared simultaneously for comparative studies.
- For normal flow filtration (NFF)
- For filter sizing and optimization studies
- Volume throughput studies with constant flow or constant pressure
- Process interaction via graphical user interface (GUI) with real-time trending feature
- Data acquisition of process data and
experiment details - Ability to enter time-stamped notes
that recorded in the data file
- Operate up to 4 trains in parallel with up to 3 pressure measurements per train with total flow by pump accumulation or connection of scales to the back panel
- Control system interfaces with GUI to streamline user interaction with the process
- Control system interfaces with up to 4 pumps for
independent control of each pump - Alarms for high pressure for each train and high delta pressures for each filter that will shut the pump off
- Real time calculation of flux and permeability based
on entered filter area within GUI - Ability to view a wide variety of trends real-time with instant export feature of current trend view
- Process data acquisition (including filter, train names and key experiment information and notes) into .CSV
file that opens directly into Excel - Pressure sensors with luer fittings connect directly
to filter test devices or flow through sensors - Expansion option for input to control system of two analytical measurements per train
(via analog 4-20mA /0-10volt signal) such as the PendoTECH Turbidity Flow Cell
Pump Selection Guide
to aid in pump
and tubing size selection
Set-up Tab where experiment details are entered
Trends View Tab:
critical data can be viewed in real-time
Constant Pressure Tab:
Time vs. volume plots and real-time throughput calculations
With this option enabled, it will maintain a user-entered maximum set point deltaP on each filter.
Advanced GUI Features Include:
- Ability to save/recall experiment setup information to save data entry time
- Control System software designed with features to prevent data loss if computer error occurs
- Ability to disable trains to enhance user interaction
Optional Accessories
Coming Soon: Pump Module
- For low flows (up to 0.2mL/min)
- Precise and low shear diaphragm pump technology
- Excellent performance againstback pressure
- Precise pump - system totalizer can be used for measure of total flow
PendoTECH Depth Filtration System
For scale up of a normal flow filtration process, a PendoTECH Process Control System can be used for process monitoring, control, and data acquisition for a complete process unit operation. Inputs include up to 3 pressure sensors per train (PendoTECH Single Use Pressure Sensors are available with upto a 1 inch flow inner diameter to handle high flow rates) with high pressure alarm monitoring. Other inputs include weight and analytical sensors with a 4-20mA output such as the PendoTECH Turbidity Flow Cell and conductivity with different flow meter options. Any pump with an analog 4-20mA speed control input and remote on/off capability can be integrated to the system. The non-invasive air detector on the inlet line can be used to stop the pump top prevent air from being pumped into the filters.
Depth Filtration / Cell Removal with PressureMAT
For monitoring of only process pressure, the PressureMAT with the PendoTECH sensors can be used for this application. There is a PressureMAT-PLUS also available with 3 pressure inputs and 1 flow meter input. A unit can also be customized for input of the PendoTECH Turbidity Flow Cell.
Please contact us at request@pendotech.com for more information.
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